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Filtered Search Results
TARGETMOL CHEMICALS INC 4-Nitroquinoline 1-oxide 1G
Also available in 1 mL, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts. Purity 98.06%
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Accela Chembio Inc 5-nitroquinoline | 100g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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5-nitroquinoline | 100g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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Ambeed AMBEED
5000948890 CP-339818 HCL 50MG
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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 25 MG
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CP 339818 hydrochloride is a non-peptide blocker for Kv1.3 and Kv1.4 channels. It also inhibits HCN channels and exhibits significantly weaker blocking effects on several other Kv channels. This compound selectively blocks Kv1.3, thereby inhibiting the activation process of human T cells, and is useful for studying the physiological functions of HCN and Kv channels.
- Kv1.3 channel blocker (IC50 = 200 nM).
- Kv1.4 channel blocker.
- Inhibits HCN channels (HCN1 and HCN4).
- Selectively inhibits human T cell activation.
- Suitable for studying physiological functions of HCN and Kv channels.
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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 1 MG
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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It can be utilized for studying the physiological functions of HCN and Kv channels.
- Non-peptide Kv1.3 and Kv1.4 channel blocker.
- Inhibits HCN channels (HCN1 and HCN4).
- Selectively blocks Kv1.3, inhibiting human T cell activation.
- Useful for studying physiological functions of HCN and Kv channels.
- Suppresses human T cell activation.
- Effectively blocks remaining outward potassium current in Kv2.1⁻/⁻ β cells.
- Inhibitory effect on HCN1 and HCN4 is weakened in low-concentration Cl- internal solution and is voltage-dependent.
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Medchemexpress LLC CP 339818 hydrochloride | 478341-55-8 | 99.6% | 340.89 g/mol | C21H25ClN2 | 5 MG
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CP 339818 hydrochloride is a small-molecule, non-peptide ion-channel inhibitor used in electrophysiology and pharmacology research. It blocks Kv1.3 and Kv1.4 channels and inhibits HCN channels, making it useful for studying Kv- and HCN-mediated currents and T-cell activation.
- Non-peptide Kv1.3 and Kv1.4 channel blocker.
- Inhibits HCN channel isoforms with micromolar potency.
- High-purity white to off-white solid suitable for research use.
- Soluble in DMSO up to 62.5 mg/mL.
- Store sealed at 4°C; in solution, keep at -80°C (up to 6 months) or -20°C (up to 1 month).
- Molecular weight 340.89 g/mol; formula C21H25ClN2.
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Medchemexpress LLC Quinidine 15 dihyd 1g | 1G
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Quinidine 15 dihyd 1g | 1G
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 25 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It can induce apoptosis and is used for malaria research.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker with an IC50 of 19.9 μM
- Induces apoptosis
- Can be used for malaria research
- Shows cytotoxicity against MES-SA cells
- Shows effects on the PTZ-induced seizure threshold in vivo
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.36% | 500 MG
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It induces apoptosis and can be utilized for malaria research. It has demonstrated cytotoxicity against MES-SA cells.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker
- Induces apoptosis
- Can be used for malaria research
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | >98.36% | 10 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, and selective cytochrome P450db inhibitor. Additionally, Quinidine is a K+ channel blocker with an IC50 of 19.9 μM and is capable of inducing apoptosis. This compound can also be utilized for malaria research.
- Antiarrhythmic agent.
- Potent, orally active, selective cytochrome P450db inhibitor.
- K+ channel blocker with an IC50 of 19.9 μM.
- Can induce apoptosis.
- Used for malaria research.
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Sigma Aldrich Fine Chemicals Biosciences Quinidine anhydrous | 56-54-2 | MFCD00135581 | 5G
Quinidine anhydrous | Mol Wt: 324.42 | 56-54-2 | MFCD00135581 | 5G
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 5 MG
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Quinidine methiodide is a metabolite of Quinidine, which is known as an antiarrhythmic agent. This product appears as a solid with a white to light yellow color.
- Metabolite of Quinidine
- Antiarrhythmic agent
- Solid appearance
- White to light yellow color
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Apexbio Technology LLC Quinidine 56-54-2 10mM (in 1mL DMSO)
Quinidine (CAS 56-54-2) is a small-molecule inhibitor targeting sodium (Na ) and potassium (K ) ion channels It is designed to inhibit these ion channel currents thereby modulating cardiac electrophysiological processes Quinidine exerts its biological activity primarily through inhibition of Na and K currents In in vitro studies quinidine demonstrates inhibitory activity with an IC50 of approximately 41 M on the transient outward potassium current (Ik) at a membrane potential of 0 mV Based on these pharmacological properties quinidine holds research potential in the fields of cardiac electrophysiology ion channel pharmacology drug metabolism and drug-drug interaction mechanisms
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Apexbio Technology LLC Quinine HCl Dihydrate 6119-47-7 10g
Quinine HCl Dihydrate is a quinoline alkaloid hydrochloride salt presented as a dihydrate form It exerts its biological activity primarily through interference with heme detoxification mechanisms within Plasmodium species disrupting parasite-mediated heme metabolism and inducing cytotoxic free heme accumulation At the molecular level quinoline derivatives may inhibit nucleic acid synthesis affecting DNA replication and transcription events during erythrocytic lifecycle stages Researchers frequently utilize Quinine HCl Dihydrate for studies on antimalarial drug mechanisms parasite resistance pathways and as a reference standard in pharmacological and pharmacokinetic assessments
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Medchemexpress LLC Quinine sulfate 50mg | 50MG
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Quinine sulfate 50mg | 50MG
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